RiverVest Venture Partners has announced it has closed its fifth fund — RiverVest Venture Fund V — with $275 million of capital commitments.

RiverVest, based in St. Louis, Mo., is a venture capital firm that targets investments in early-stage biopharma and medical device companies.

Fund V is RiverVest’s largest fund to date. With the fifth fund, which was oversubscribed, RiverVest’s total assets under management now exceed $1.6 billion.

The firm noted that it has invested in 55 companies and founded 15 companies.